Royal Air Force Typhoon jets have conducted a mission with France's air force in a joint strike on an hidden munitions depot in Syria employed by the IS group, per a report from the British defence ministry.
The site, pinpointed through intelligence, was assessed as containing munitions and bombs, the statement said, and was situated in mountainous terrain just above Palmyra in Syria's central region.
"Our fighter planes used precision-guided Paveway IV munitions to strike a series of access tunnels down to the site... preliminary assessments indicate the objective was successfully hit," officials stated.
There was no indication of any civilian casualties in the attack on Saturday evening and each participating jet returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
The Islamic State group - also known as the so-called Islamic State - established jihadist rule over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This action shows our UK leadership, and determination to stand shoulder to shoulder with allied nations, to eradicate any resurgence of IS and their harmful and extremist ideologies in the region," UK Defence Secretary John Healey said.
UK warplanes have performed surveillance missions over Syrian airspace to "forestall any efforts to regroup" of the group following its defeat at the battle of Baghuz in 2019, the MoD reported.
"I want to thank the personnel of the UK armed forces participating in this strike for their expertise and their valour," Healey said. "They were part of thousands of British troops stationed over Christmas and New Year. This action, to remove militants who pose a risk to our safety, shows how our armed forces are ready to step up, continuously, protecting the UK within its borders and influential overseas."
In December, the US military executed what it called a "massive strike" against Daesh sites in the country, following an attack claimed the lives of two US troops and a local interpreter in the Palmyra area.
The UN reports Daesh still has between 5,000 and 7,000 militants in both countries.